Sermorelin

Name: Sermorelin
SKU: 1017
Availability: InStock

$65.00

Product Name: Sermorelin Acetate
Synonyms: GRF (1-29), Growth Hormone Releasing Factor 1-29
CAS Number: 86168-78-7
Molecular Formula: C149H246N44O42S
Molecular Weight: 3357.9 g/mol
Purity: ≥98% (HPLC Verified)
Form: Lyophilized White Powder
Storage (Lyophilized): -20°C, dry, and away from light
Storage (Reconstituted): 2–8°C; use within 10–20 days
Intended Use: For Laboratory Research Only – Not for Human Consumption

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Sermorelin

Sermorelin, also known as GRF (1-29), is a synthetic peptide analog of the endogenous growth hormone-releasing hormone (GHRH). It comprises the first 29 amino acids of natural GHRH – the portion responsible for its biological activity – and is widely used in scientific studies focusing on growth hormone (GH) secretion, IGF-1 regulation, and endocrine pathway stimulation.

Unlike synthetic growth hormone injections that override natural hormone cycles, Sermorelin stimulates the body’s own production of GH, making it ideal for research focused on physiological GH pulse restoration.

⚙️ Key Features

✅ 98%+ HPLC-verified purity
✅ Short-acting, natural GH secretion analog
✅ Does not suppress pituitary function
✅ Excellent for combining with GHRPs like Ipamorelin or GHRP-2
✅ Manufactured in GMP-certified facilities

📚 Mechanism of Action

Sermorelin binds to GHRH receptors in the anterior pituitary, triggering the natural secretion of growth hormone in a pulsatile pattern. This pulsatility mimics the body’s natural GH rhythms and supports healthy feedback regulation of the GH/IGF-1 axis.

Its short half-life (approx. 30 minutes) allows for precise, time-controlled studies, especially when paired with GHRPs for synergistic GH pulses.

🔬 Primary Research Applications

💪 Anabolic & GH Secretion Studies
Used to evaluate natural growth hormone production, muscle repair, and GH/IGF-1 signaling.

🧬 Endocrine & Pituitary Function Research
Ideal for testing feedback mechanisms, hormonal balance, and GH suppression models.

🧠 Aging & Cognitive Function Studies
Evaluated for its effects on GH decline with age, cognition, sleep quality, and tissue regeneration.

🔥 Body Composition & Fat Metabolism Models
Assessed in research on lipolysis, visceral fat mobilization, and lean mass retention.

🔄 Sermorelin vs. CJC-1295 (with DAC)

Feature	Sermorelin (GRF 1-29)	CJC-1295 DAC
Half-Life	~30 minutes	~6–8 days
GH Release Pattern	Short, pulsatile	Sustained
Injection Frequency	Multiple daily (for pulse)	1–2x per week
Control Level	High (precise timing)	Lower (long-acting)
Best Use Case	Acute GH pulse studies	Long-term GH elevation

🧪 Reconstitution & Storage (Research Use Only)

Diluent: Bacteriostatic Water (BAC)
Reconstituted Storage: Refrigerate at 2–8°C
Shelf Life (Reconstituted): 10–20 days
Do Not Freeze Reconstituted Solution

📦 What’s Included

Certificate of Analysis (CoA)
Safety Data Sheet (SDS)
Lot Number & Manufacturing Batch
Lyophilized vial in vacuum-sealed packaging
Cold-chain shipping available on request

🚫 Disclaimer

Sermorelin is for scientific and laboratory research purposes only. It is not intended for human use, clinical trials, or therapeutic applications. Buyers must be qualified researchers or institutions.

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