MOTS-c 

MOTS-c is a mitochondrial-derived peptide (MDP), encoded by a small open reading frame within mitochondrial DNA. It plays a critical role in cellular energy homeostasis, insulin sensitivity, stress resistance, and metabolic regulation.

MOTS-c is particularly interesting in aging and longevity research, where it’s shown to enhance mitochondrial function, improve exercise performance, and delay age-related metabolic decline in preclinical models.

ChemDope supplies MOTS-c in 10mg lyophilized vials, ideal for researchers studying bioenergetics, metabolic health, and mitochondrial signaling.

⚙️ Key Features

• ✅ High-purity MOTS-c peptide (≥98% verified by HPLC)

• ✅ Supplied in 10mg research-grade vials

• ✅ Mitochondrial-derived signaling peptide

• ✅ Investigated in metabolic and longevity models

• ✅ Ideal for insulin sensitivity, mitochondrial, and stress studies

• ✅ CoA included, GMP-compliant production

???? Mechanism of Action

MOTS-c acts primarily via AMPK activation, which plays a pivotal role in regulating cellular metabolism, energy balance, and stress response. It promotes glucose uptake, enhances fatty acid oxidation, and supports mitochondrial integrity.

???? Research Applications 

???? Mitochondrial Function Studies
Used to investigate bioenergetic regulation, mitochondrial gene signaling, and oxidative stress response.

???? Metabolic Syndrome & Insulin Sensitivity
Valuable in studies on type 2 diabetes, glucose homeostasis, and lipid regulation.

???? Aging & Longevity Models
Explored in age-related metabolic decline, exercise capacity, and lifespan extension research.

???? Fat Oxidation & Weight Regulation
Supports fat loss research by increasing fatty acid oxidation and reducing lipid accumulation.

???? Reconstitution & Storage Instructions

• Recommended Diluent: Bacteriostatic Water (BAC)

• Suggested Volume: 1–2mL per 10mg vial

• Storage (Lyophilized): -20°C, light-protected

• Storage (Reconstituted): 2–8°C for up to 30 days

• Avoid multiple freeze-thaw cycles

• Use under sterile laboratory conditions

???? What’s Included

• 1 Vial of 10mg

• Certificate of Analysis (CoA)

• Batch-specific purity data

• Sterile, sealed packaging

• Cold-chain shipping available

???? Disclaimer

MOTS-c is intended for laboratory research purposes only. Not for human consumption, medical, or veterinary use. Only qualified researchers and institutions may use this compound.