MOTS-c 

MOTS-c is a mitochondrial-derived peptide (MDP), encoded by a small open reading frame within mitochondrial DNA. It plays a critical role in cellular energy homeostasis, insulin sensitivity, stress resistance, and metabolic regulation.

MOTS-c is particularly interesting in aging and longevity research, where it’s shown to enhance mitochondrial function, improve exercise performance, and delay age-related metabolic decline in preclinical models.

ChemDope supplies MOTS-c in 10mg lyophilized vials, ideal for researchers studying bioenergetics, metabolic health, and mitochondrial signaling.

⚙️ Key Features

• ✅ High-purity MOTS-c peptide (≥98% verified by HPLC)

• ✅ Supplied in 10mg research-grade vials

• ✅ Mitochondrial-derived signaling peptide

• ✅ Investigated in metabolic and longevity models

• ✅ Ideal for insulin sensitivity, mitochondrial, and stress studies

• ✅ CoA included, GMP-compliant production

📚 Mechanism of Action

MOTS-c acts primarily via AMPK activation, which plays a pivotal role in regulating cellular metabolism, energy balance, and stress response. It promotes glucose uptake, enhances fatty acid oxidation, and supports mitochondrial integrity.

🔬 Research Applications 

🧪 Mitochondrial Function Studies
Used to investigate bioenergetic regulation, mitochondrial gene signaling, and oxidative stress response.

🧬 Metabolic Syndrome & Insulin Sensitivity
Valuable in studies on type 2 diabetes, glucose homeostasis, and lipid regulation.

🧓 Aging & Longevity Models
Explored in age-related metabolic decline, exercise capacity, and lifespan extension research.

🔥 Fat Oxidation & Weight Regulation
Supports fat loss research by increasing fatty acid oxidation and reducing lipid accumulation.

🧪 Reconstitution & Storage Instructions

• Recommended Diluent: Bacteriostatic Water (BAC)

• Suggested Volume: 1–2mL per 10mg vial

• Storage (Lyophilized): -20°C, light-protected

• Storage (Reconstituted): 2–8°C for up to 30 days

• Avoid multiple freeze-thaw cycles

• Use under sterile laboratory conditions

📦 What’s Included

• 1 Vial of 10mg

• Certificate of Analysis (CoA)

• Batch-specific purity data

• Sterile, sealed packaging

• Cold-chain shipping available

🚫 Disclaimer

MOTS-c is intended for laboratory research purposes only. Not for human consumption, medical, or veterinary use. Only qualified researchers and institutions may use this compound.