NAD+ (500mg / 1000mg) – High-Purity Nicotinamide Adenine Dinucleotide for Research Use Only

NAD+, short for Nicotinamide Adenine Dinucleotide, is a naturally occurring coenzyme present in all living cells. It plays a crucial role in cellular respiration, energy production, mitochondrial function, DNA repair, and aging-related processes. Our high-purity NAD+ is available in 500mg and 1000mg research-grade powder forms, ideal for use in laboratory experiments, biochemical assays, and longevity research.

NAD+ levels naturally decline with age, and this depletion is linked to a range of age-related disorders, including metabolic syndromes, neurodegenerative diseases, and reduced cellular resilience. As such, NAD+ supplementation in in vitro and in vivo models has become a critical focus in life extension and regenerative biology studies.

💡 Why Researchers Choose Our NAD+:

• ≥ 99% pure pharmaceutical-grade compound

• Offered in two sizes: 500mg and 1000mg

• Ideal for studies on cell metabolism, mitochondrial health, and NAD+ recycling pathways

• Packaged in airtight, UV-protective vials to ensure compound stability

• Produced under strict GMP-compliant lab conditions

• Backed by COA (Certificate of Analysis) on request

🔬 Scientific Background of NAD+:

NAD+ exists in two forms:

• Oxidized (NAD+)

• Reduced (NADH)

In its oxidized form, NAD+ serves as an electron transporter in key metabolic pathways like glycolysis, the TCA (Krebs) cycle, and oxidative phosphorylation. In this role, NAD+ enables cells to generate adenosine triphosphate (ATP)—the essential “energy currency” of life.

Beyond energy production, NAD+ is also required for:

• DNA damage repair via activation of PARP enzymes

• Epigenetic regulation through Sirtuin activation (SIRT1–SIRT7)

• Calcium signaling modulation

• Mitochondrial biogenesis

• Stem cell maintenance

• Circadian rhythm synchronization

As NAD+ levels decline with age, the performance of these systems deteriorates, which is why NAD+ restoration strategies are being explored in both clinical and non-clinical research settings.

🧬 Research Applications of NAD+:

Researchers commonly use NAD+ in experiments related to:

• 🔬 Longevity & anti-aging interventions

• 🧠 Neuroprotection in Alzheimer’s, Parkinson’s, and MS models

• ⚡ Mitochondrial efficiency and energy metabolism studies

• 🧪 Sirtuin and AMPK pathway activation

• 💉 NAD+ replacement therapy in NAD-deficient organisms

• 📈 Epigenetic modulation and chromatin structure studies

• 🧫 Cellular senescence and rejuvenation research

🧾 Technical Specifications:

⚗️ Instructions for Handling and Use:

• Reconstitute only under sterile laboratory conditions

• Use bacteriostatic water or sterile saline if solution preparation is needed

• Store unopened vials in a cool, dark place

• Once reconstituted, refrigerate and use within 30 days

• Always wear proper lab PPE when handling the substance

⚠️ Safety & Legal Disclaimer:

This product is sold strictly for laboratory research purposes only. It is not intended for human ingestion, therapeutic use, or veterinary application. Misuse of this product may result in legal penalties and health risks. Buyer assumes full responsibility for use and storage in accordance with local, state, and federal laws.