PT-141

PT-141, also known as Bremelanotide, is a synthetic melanocortin receptor agonist derived from Melanotan II. It is primarily used in research exploring sexual dysfunction, libido enhancement, and neurohormonal signaling. PT-141 is distinct from traditional PDE5 inhibitors (like sildenafil) because it works through the central nervous system rather than vascular pathways.

In laboratory settings, PT-141 has demonstrated increased sexual arousal in both male and female subjects, making it a key peptide in hypoactive sexual desire disorder (HSDD) research.

⚙️ Key Features

• ✅ 10mg high-purity lyophilized peptide

• ✅ ≥98% purity, HPLC verified

• ✅ Acts on melanocortin receptors (MC3, MC4)

• ✅ Central-acting sexual function peptide

• ✅ Non-hormonal mechanism of action

• ✅ Manufactured in GMP-certified facilities

📚 Mechanism of Action

PT-141 primarily binds to melanocortin receptors MC3 and MC4 in the hypothalamus of the brain. This action stimulates the dopaminergic pathways associated with sexual desire, arousal, and pleasure.

🔬 Research Applications

🧠 Libido and Arousal Studies
Explored for its ability to increase sexual motivation and responsiveness in both male and female animal models.

🩺 Hypoactive Sexual Desire Disorder (HSDD)
Evaluated in preclinical models of low libido and sexual apathy.

🧬 Neurohormonal Signaling Research
Used in studies focused on central melanocortin pathways related to mood, reward, and behavior.

💡 Sexual Dysfunction Alternatives
A potential option in models where traditional vasodilators show limited efficacy or contraindications.

🔄 PT-141 vs. Traditional PDE5 Inhibitors

🧪 Reconstitution & Storage Guidelines

• Reconstitution Fluid: Bacteriostatic Water (BAC)

• Recommended Volume: 2–3mL for 10mg vial

• Storage (Lyophilized): -20°C, in light-resistant vial

• Storage (Reconstituted): 2–8°C; stable for up to 30 days

• Do not freeze once reconstituted

• Avoid prolonged exposure to light and moisture

📦 What’s Included

• 1 vial of PT-141 (Bremelanotide) 10mg

• Certificate of Analysis (CoA)

• Batch tracking and lot verification

• Tamper-proof packaging

• Cold-chain shipping available

🚫 Disclaimer

PT-141 is intended strictly for laboratory research use only. It is not approved for human use, consumption, or therapeutic application. Only licensed researchers and institutions may purchase or handle this compound.