MGF (Mechano Growth Factor)

MGF (Mechano Growth Factor) is a biologically active splice variant of Insulin-like Growth Factor-1 (IGF-1). It is naturally produced in muscle tissue in response to mechanical overload or muscle damage. In peptide form, MGF has become a focal point in research studying muscle repair, hypertrophy, and regeneration.

Unlike IGF-1 LR3, which exerts long-term systemic effects, MGF initiates localized muscle growth by activating satellite cells, leading to muscle fiber repair and proliferation. This unique mechanism makes MGF highly relevant in preclinical research involving muscle wasting, injury recovery, and anabolic signaling.

Mechanism of Action

MGF is expressed in skeletal muscle following physical stress or injury. It functions by:

• Stimulating the activation of muscle satellite cells

• Promoting myoblast proliferation

• Increasing the rate of muscle regeneration

• Enhancing protein synthesis and nitrogen retention

MGF is often studied in combination with IGF-1 LR3, with MGF responsible for initiating growth and LR3 sustaining it over time.

Primary Research Applications

💪 Muscle Repair & Regeneration Studies
Ideal for evaluating muscle recovery after trauma, overtraining, or immobilization.

🧬 Anabolic Research Models
Explored in studies involving muscle hypertrophy, resistance training adaptations, and anti-catabolic therapy.

🧠 Neuromuscular Health
MGF is under investigation for its potential neuroprotective effects and role in motor neuron survival.

🩺 Anti-Aging and Longevity Studies
As GH and IGF-1 levels decline with age, MGF is used in aging models to assess muscle preservation and hormonal feedback loops.

Suggested Reconstitution (For Research Use Only)

• Solvent: Sterile Bacteriostatic Water or Acetic Acid (0.6%)

• Dosage Range (Experimental Use): Varies by protocol

• Storage:

  • Lyophilized: -20°C

  • Reconstituted: 2–8°C, use within 10–20 days

Do not freeze reconstituted solution.

Why Choose ChemDope.com for MGF?

• ✅ Pharmaceutical-Grade Peptide (≥98% Purity)

• ✅ Independently Lab-Tested (HPLC + MS)

• ✅ Detailed Batch CoAs & SDS Provided

• ✅ Cold Chain Handling & Discreet Packaging

• ✅ Dedicated Research Support for Labs & Institutions

Disclaimer

MGF is intended strictly for in vitro research and laboratory use. It is not approved for human or animal consumption, therapeutic use, or clinical trials. All customers must be qualified professionals operating within a legal and ethical research environment.