IGF-1 LR3 Peptide (Insulin-Like Growth Factor) 0.1mg & 1mg Vials

IGF-1 LR3 is a synthetic analog of human Insulin-Like Growth Factor 1, engineered for increased potency and a significantly longer half-life. The substitution of arginine at position 3 and the 13 amino acid N-terminal extension grants resistance to IGF-binding proteins, allowing for enhanced biological activity.

It plays a vital role in cell growth, muscle hypertrophy, tissue regeneration, and anti-aging research, making it one of the most widely studied peptides in biological repair, performance, and endocrine regulation models.

ChemDope offers  ultra-pure 0.1mg and 1mg vials suitable for advanced lab use.

⚙️ Key Features

• ✅ Long-acting IGF-1 analog (LR3 variant)

• ✅ Available in 0.1mg and 1mg vial options

• ✅ Superior receptor activation compared to native

• ✅ Promotes muscle regeneration and cellular growth

• ✅ GMP-manufactured and HPLC verified (≥98%)

• ✅ Certificate of Analysis (CoA) included

📚 Mechanism of Action

IGF-1 LR3 activates the receptor, triggering the PI3K/AKT and MAPK/ERK pathways responsible for:

• Cellular proliferation and differentiation

• Muscle satellite cell activation

• Increased amino acid uptake and protein synthesis

• Glucose metabolism regulation

• Tissue healing and neuroprotection

Because LR3 is resistant to IGF-binding proteins, its biological availability is 3x to 5x higher than native IGF-1.

🔬 Research Applications

💪 Muscle Growth & Regeneration Studies
Used in myogenesis, muscle injury, and muscle-wasting disease models.

🧬 Cell Proliferation & Repair
Valuable in tissue engineering, wound healing, and stem cell research.

🧠 Neuroprotection & Cognitive Research
Investigated in models of brain injury, neuroplasticity, and aging-related decline.

🧫 Endocrine & Metabolic Research
Applied in glucose utilization, insulin signaling, and growth regulation studies.

🧪 Reconstitution & Storage Instructions

• Diluent: Bacteriostatic Water (BAC) or 0.6% Acetic Acid (recommended)

• Reconstitution Volume:

  • For 0.1mg: 1mL

  • For 1mg: 1–2mL depending on concentration need

• Storage (Lyophilized): -20°C in dark

• Storage (Reconstituted): 2–8°C for up to 30 days

• Do not freeze after reconstitution; avoid repeated thaw cycles

📦 What You Receive

• 1 vial of IGF-1 LR3 (0.1mg or 1mg)

• Certificate of Analysis (CoA)

• Batch-specific purity and quality documents

• Cold-pack shipping (optional)

🚫 Disclaimer

It intended for laboratory research only. It is not approved for human use, therapeutic purposes, or veterinary application. Use only in sterile, controlled laboratory environments.