Gonadorelin 2mg / 5mg / 10mg

Gonadorelin is a synthetic gonadotropin-releasing hormone (GnRH), also referred to as luteinizing hormone-releasing hormone (LHRH). It is a decapeptide that mimics natural GnRH released by the hypothalamus to regulate the hypothalamic-pituitary-gonadal (HPG) axis.

Gonadorelin is used in research exploring fertility, puberty onset, hormone regulation, and gonadotropin secretion, especially in studies involving the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the anterior pituitary.

⚙️ Key Features

• ✅ ≥98% peptide purity (HPLC-verified)

• ✅ Synthetic GnRH analog with high biological activity

• ✅ Used in male and female reproductive studies

• ✅ Rapid onset and short half-life for controlled dosing

• ✅ Stable under proper storage conditions

📚 Mechanism of Action

Gonadorelin binds to GnRH receptors in the anterior pituitary, stimulating the release of LH and FSH. These hormones then act on the gonads (testes or ovaries) to regulate the production of testosterone, estrogen, and progesterone, thus controlling reproduction, development, and secondary sex characteristics.

In research models, it is often used to:

• Stimulate gonadotropin secretion

• Study endocrine feedback loops

• Induce ovulation or spermatogenesis

• Investigate puberty disorders and hormone deficiencies

🔬 Primary Research Applications

🧬 Reproductive Endocrinology
Used to study the function and disorders of the HPG axis, including fertility, delayed puberty, and hypogonadism.

🧪 Hormone Regulation Research
Explores how LH and FSH influence gonadal development, ovulation, and steroidogenesis.

🩺 Fertility & Ovulation Models
Used in female models to mimic ovulatory triggers and understand menstrual cycle regulation.

💉 Pituitary Stimulation Studies
Assists in diagnosing pituitary responsiveness in preclinical settings.

🔄 Comparison: Gonadorelin vs. Leuprolide (GnRH Agonist)

🧪 Reconstitution & Storage (For Research Use Only)

• Diluent: Sterile Bacteriostatic Water (BAC)

• Storage (Lyophilized): -20°C

• Storage (Reconstituted): 2–8°C for up to 30 days

• Do Not Freeze reconstituted solution

• Protect from light and moisture

📦 What’s Included

• Pharmaceutical-grade lyophilized peptide

• Certificate of Analysis (CoA)

• Safety Data Sheet (SDS)

• Secure, tamper-proof vial

• Cold-chain shipping available upon request

🚫 Disclaimer

Gonadorelin is intended strictly for laboratory research use only. It is not for human consumption, therapeutic use, or clinical trials. Only licensed institutions and qualified researchers may purchase and handle this compound.